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Protini Polypeptide Cream
Moisturiser50 mlLight cream
Drunk Elephant logoDrunk Elephant

Protini Polypeptide Cream

A good peptide moisturiser at a price that four cheaper products make very hard to justify

3.93.9 out of 5
$68
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Suits
NormalCombinationDry
Targets
FirmnessDullnessBarrier support
Key ingredients
Signal peptidesAmino acidsPygmy waterlily
Protini Polypeptide Cream specifications
Key actives9 signal peptides, 8 amino acids
FragranceNone
PackagingAirless pump
Cost per ml≈ $1.36

Protini Polypeptide Cream review

What it does

A peptide moisturiser. The nine signal peptides and eight amino acids are there to support the skin's own repair signalling, and the base is a competent, genuinely fragrance-free light cream that most skin types tolerate.

It works. That is not the argument against it.

The price problem

At roughly $1.36 per millilitre, this costs about eight times what CeraVe's Moisturizing Cream costs per ml, and the honest comparison is uncomfortable:

ProtiniCeraVe Moisturizing Cream
Price per ml≈ $1.36≈ $0.04
Barrier repairGoodExcellent (three ceramides)
Fragrance-freeYesYes
PeptidesYesNo
Evidence for peptides in leave-on skincareModest

Peptides are real, and the evidence for topical signal peptides producing visible firming is considerably weaker than the marketing around them implies. You are paying a large premium for the least-proven part of the formula.

Where it genuinely earns points

The airless pump is the right packaging for an unstable formula and better than most competitors at any price. The range is properly fragrance-free, which is rarer at the prestige tier than it should be. And the texture is genuinely pleasant.

Who should buy it

Someone for whom the price is not a consideration and who wants a curated fragrance-free routine. If you are weighing value at all, a ceramide cream plus a well-formulated serum will do more for a fraction of the cost.

Disclosure

Drunk Elephant is a paid partner of TrusteDiva. That did not change this review — the brand holds the lowest value score on the site.

The verdict

Pros

  • Genuinely fragrance-free and essential-oil-free
  • Airless pump protects the formula properly
  • Pleasant, light texture that layers well
  • Cruelty-free

Cons

  • About eight times the per-ml cost of a better barrier cream
  • Evidence for topical signal peptides is weaker than the marketing implies
  • Does less for a damaged barrier than a $17 ceramide cream

Protini Polypeptide Cream FAQs

Rarely. It is a well-made, pleasant, fragrance-free moisturiser, but a $17 ceramide cream does more measurable barrier work, and the peptide evidence is not strong enough to justify the gap. Buy it if budget is irrelevant to you.

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